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浙江大学学报(医学版)  2015, Vol. 44 Issue (3): 344-348    DOI: 10.3785/j.issn.1008-9292.2015.05.17
综述     
丙型肝炎病毒在辅助生殖技术中的存在与垂直传播
尤佳莉, 朱依敏
浙江大学医学院附属妇产科医院生殖内分泌科, 浙江 杭州 310006
The state of HCV infection and vertical transmission during assisted reproductive technology
YOU Jia-li, ZHU Yi-min
Department of Reproductive Endocrinology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China
 全文: PDF(563 KB)   HTML (
摘要:

垂直传播是儿童感染丙型肝炎病毒(HCV)的主要方式,近年来受到广泛关注。随着辅助生殖技术的发展,越来越多的HCV感染不孕夫妇寻求辅助生殖技术治疗以获得后代。辅助生殖技术过程中HCV的垂直传播现象仍不可避免,了解HCV在母体和胚胎内的存在与风险,有利于在解决生育问题的同时更好地控制HCV的垂直传播,预防儿童感染。

关键词: 肝炎病毒属/免疫学肝炎丙型/传播疾病传播垂直生殖技术辅助卵母细胞胎儿疾病综述    
Abstract:

Vertical transmission is the major route of HCV infection in children and draws much attention recently. With the development of assisted reproductive technology (ART), more and more HCV-serodiscordant infertile couples seek assisted reproduction treatment. Vertical transmission of HCV in ART cannot be avoided. Understanding the state of HCV infection of oocyte and embryo is helpful to solve the fertility problem and to control mother-to-child transmission.

Key words: Hepacivirus/immunology    Hepatitis C/transmission    Disease transmission, vertical    Reproductive techniques, assisted    Oocytes    Fetal diseases    Review
收稿日期: 2014-11-26 出版日期: 2015-05-25
:  R512.6  
基金资助:

浙江省自然科学基金 (Y206148)

通讯作者: 朱依敏(1964-),女,博士,主任医师,主要从事生殖内分泌临床研究;E-mail:zhuyim@zju.edu.cn;http://orcid.org/0000-0002-9667-3677     E-mail: zhuyim@zju.edu.cn
作者简介: 尤佳莉(1989-),女,硕士研究生,主要从事滋养细胞与早期流产关系的研究;E-mail:21218199@zju.edu.cn;http://orcid.org/0000-0001-8373-3725
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引用本文:

尤佳莉, 朱依敏. 丙型肝炎病毒在辅助生殖技术中的存在与垂直传播[J]. 浙江大学学报(医学版), 2015, 44(3): 344-348.

YOU Jia-li, ZHU Yi-min. The state of HCV infection and vertical transmission during assisted reproductive technology. Journal of ZheJiang University(Medical Science), 2015, 44(3): 344-348.

链接本文:

http://www.zjujournals.com/med/CN/10.3785/j.issn.1008-9292.2015.05.17        http://www.zjujournals.com/med/CN/Y2015/V44/I3/344

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