Please wait a minute...
浙江大学学报(医学版)  2013, Vol. 42 Issue (2): 232-236    DOI: 10.3785/j.issn.1008-9292.2013.02.016
综述     
儿童漏斗胸Nuss术后镇痛的研究进展
周晨1,金海燕1,李建华2,胡智勇1
浙江大学医学院附属儿童医院1.麻醉科、2.心胸外科,浙江 杭州 310003
Research progress on postoperative analgesia for pectus excavatum in pediatric patients after Nuss procedure
ZHOU Chen1, JIN Hai-Yan1, LI Jian-Hua,2 HU Zhi-Yong1
1.Department of Anesthesiology,2.Department of Cardiothoracic Surgery,The AffiliatedChildren′s Hospital,Zhejiang University School of Medicine,Hangzhou 310003,China
 全文: PDF(535 KB)   HTML (
摘要:

漏斗胸是儿童中最常见的先天性胸壁畸形,而Nuss术是目前最先进的矫形术式。其优点是避免了过去Ravitch术带来的巨大创伤,但所造成的术后疼痛的严重程度却不亚于开胸术。因此,合理有效的术后镇痛就显得十分重要。文中就影响儿童漏斗胸Nuss术后疼痛的因素、镇痛方式和相关并发症,以及药物不良反应的研究进展予以综述。

关键词: 漏斗胸/外科学疼痛手术后/预防和控制镇痛/方法Nuss术不良反应多模式镇痛    
Abstract:

Pectus excavatum is the common congenital chest wall deformity in children,and Nuss procedure is the conventional surgical treatment for this disease.Nuss procedure is superior to Ravitch correction for it is less harmful in terms of the surgical technique.However,Nuss procedure is associated with severe postoperative pain,thus adequate postoperative analgesia is important.In this review,factors that influence the postoperative pain after Nuss procedure,the pain managements,the related complications and the side effects of drugs are discussed.

Key words: Funnel chest/surgery    Pain,postoperative/prevention &    control    Analgesias/methods    Nuss procedure    adverse effect    multimode analgesia
收稿日期: 2012-02-16 出版日期: 2013-03-25
:  R 614  
基金资助:

浙江省教育厅科研项目(Y201017446).

通讯作者: 胡智勇(1964-),男,硕士,主任医师,硕士生导师,主要研究领域:吸入麻醉药对脑、心脏等重要脏器的保护作用及循环呼吸功能的监测;     E-mail: huzynet@yahoo.com
作者简介: 周晨(1985-),男,硕士,住院医师,从事小儿麻醉与疼痛治疗工作.
服务  
把本文推荐给朋友
加入引用管理器
E-mail Alert
RSS
作者相关文章  
周晨
金海燕
李建华
胡智勇

引用本文:

周晨, 金海燕, 李建华, 胡智勇. 儿童漏斗胸Nuss术后镇痛的研究进展[J]. 浙江大学学报(医学版), 2013, 42(2): 232-236.

ZHOU Chen, JIN Hai-Yan, LI Jian-Hua, HU Zhi-Yong. Research progress on postoperative analgesia for pectus excavatum in pediatric patients after Nuss procedure. Journal of ZheJiang University(Medical Science), 2013, 42(2): 232-236.

链接本文:

http://www.zjujournals.com/med/CN/10.3785/j.issn.1008-9292.2013.02.016        http://www.zjujournals.com/med/CN/Y2013/V42/I2/232

[1]CASTELLANI C,SCHALAMON J,SAXENA AK,et al.Early complications of the Nuss procedure for pectus excavatum:a prospective study [J].Pediatr Surg Int,2008,24(6):659-666.
[2]VEGUNTA R K,PACHECO P E,WALLACE L J,et al.Complications associated with the Nuss procedure:continued evolution of the learning curve [J].Am J Surg,2008,195(3):313-317.
[3]GORETSKY M J,KELLY R E J R,CROITORU D,et al.Chest wall anomalies:pectus excavatum and pectus carinatum [J].Adolesc Med,2004,15(3):445-471.
[4]LAM M W C,KLASSEN A F,MONTGOMERY C J,et al.Quality-of-life outcomes after surgical correction of pectus excavatum:a comparison of the Ravitch and Nuss procedures [J].J Pediatr Surg,2008,43(5):819-825.
[5]COLN E,CARRASCO J,COLN D.Demonstrating relief of cardiac compression with the Nuss minimally invasive repair for pectus excavatum [J].J Pediatr Surg,2006,41(4):683-686.
[6]LAWSON M L,MELLINS R B,TABANGIN M,et al.Impact of pectus excavatum on pulmonary function before and after repair with the Nuss procedure [J].J Pediatr Surg,2005,40(1):174-180.
[7]NUSS D,KELLY RE J R,CROITORU D P,et al.A 10-year review of a minimally invasive technique for the correction of pectus excavatum. [J].Pediatr Surg,1998,33(4):545-552.
[8]RAVITCH M M.The operative treatment of pectus excavatum [J].Ann Surg,1949,129(4):429-444.
[9]PILEGAARD H K,GROSEN K.Editorial comment Postoperative pain location following the Nuss procedure-what is the evidence and does it make a difference [J].Eur J Cardiothorac Surg,2010,38(2):203-208.
[10]NAGASO T,MIYAMOTO J,KOKAJI K,et al.Double-bar application decreases postoperative pain after the Nuss procedure [J].J Thorac Cardiovasc Surg,2010,140(1):39-44.
[11]HURME T,SAVOLA J,VILKKI V.Minimally invasive repair for treating pectus excavatum early results [J].Scand J Surg,2008,97(1):63-70.
[12]SHU Q,SHI Z,XU WZ,et al.Experience in minimally invasive Nuss operation for 406 children with pectus excavatum [J].World J Pediatr,2011,7(3):257-261.
[13]TADDIO A,KATZ J,ILERSICH A L,et al.Effect of neonatal circumcision on pain response during subsequent routine vaccination [J].Lancent,1997,349(9052):599-603.
[14]GROSEN K,PFEIFFER-JENSEN M,PILEGAARD H K.Postoperative consumption of opioid analgesics following correction of pectus excavatum is influenced by pectus severity:a single-centre study of 236 patients undergoing minimally invasive correction of pectus excavatum [J].Eur J Cardiothorac Surg,2010,37(4):833-839.
[15]WEBER P G,HUEMMER H P,REINGRUBER B.Forces to be overcome in correction of pectus excavatum [J].J Thorac Cardiovasc Surg,2006,132(6):1369-1373.
[16]NAGASAO T,MIYAMOTO J,TAMAKI T,et al.Stress distribution on the thorax after the Nuss procedure for pectus excavatum results in different patterns between adult and child patients [J].J Thorac Cardiovasc Surg,2007,134(6):1502-1507.
[17]NAGASAO T,MIYAMOTO J,ICHIHARA K,et al.Age-related change of postoperative pain location after Nuss procedure for pectus excavatum [J].Eur J Cardiothorac Surg,2010,38(2):203-208.
[18]HALLER J A J R,KRAMER S S,LIETMAN S A.Use of CT scans in selection of patients for pectus excavatum surgery:a preliminary report [J].J Pediatr Surg,1987,22(10):904-906.
[19]SCHALAMON J,POKALL S,WINDHABER J,et al.Minimally invasive correction of pectus excavatum in adult patients [J].J Thorac Cardiovasc Surg,2006,132(3):524-529.
[20]KIM D O H,HWANG J J,LEE M K.Analysis of the Nuss procedure for pectus excavatum in different age groups [J].Ann Thorac Surg,2005,80:1073-1077.
[21]YAPICI D,ATICI S,ALIC M,et al.Morphine added to local anaesthetic improves epidural analgesia in minimally invasive Nuss operation for pectus excavatum [J].Br J Anaesth,2008:100(2),280.
[22]WALASZCZYK M,KNAPIK P,MISIOLEK H,et al.Epidural and opioid analgesia following the Nuss procedure [J].Med Sci Monit,2011,17(11):PH81-86.
[23]SOLIMAN I E,APUYA J S,FERTAL K M,et al.Intravenous versus epidural analgesia after surgical repair of pectus excavatum [J].Am J Ther,2009,16(5):389-403.
[24]BUTKOVIC D,KRALIK S,MATOLIC M,et al.Postoperative analgesia with intravenous fentanyl PCA vs epidural block after thoracoscopic pectus excavatum repair in children [J].Br J Anaesth,2007,98(5):677-681.
[25]WEBER T,MATZL J,ROKITANSKY A,et al.Superior postoperative pain relief with thoracic epidural analgesia versus intravenous patient-controlled analgesia after minimally invasive pectus excavatum repair [J].J Thorac Cardiovasc Surg,2007,134(4):865-870.
[26]CUCCHIARO G,ADZICK S N,ROSE J B,et al.A comparison of epidural bupivacaine-fentanyl and bupivacaine-clonidine in children undergoing the Nuss procedure [J].Anesth Analg,2006,103(2):322-327.
[27]RUGYTE D C,KILDA A,KARBONSKIENE A,et al.Systemic postoperative pain management following minimally invasive pectus excavatum repair in children and adolescents:a retrospective comparison of intravenous patient-controlled analgesia and continuous infusion with morphine [J].Pediatr Surg int,2010,26(7):665-669.
[28]QING Peishun,Jin Lexiao,WANG Jianguang,et al(秦培顺,金乐潇,王建光,等).Effects of different doses of fentanyl in intravenous patient-controlled analgesia after pectus excavatum operation of children \[J\].The Journal of Practical Medicine(实用医学杂志),2009,25(20):3469-3471.(in Chinese)
[29]ST PETER S D,WEESNER K A,WEISSEND E E,et al.Epidural vs patient-controlled analgesia for postoperative pain after pectus excavatum repair a prospective randomized trial [J].Pediatr Surg,2012,47(1):148-153.
[30]BEN-DAVID B,SWANSON J,NELSON J B,et al.Multimodal analgesia for radical prostatectomy provides better analgesia and shortens hospital stay [J].J Clin Anesthesia,2007,19(4):264-268.
[31]ST PETER S D,WEESNER K A,SHARP R J,et al.Is epidural anesthesia truly the best pain management strategy after minimally invasive pectus excavatum repair [J].J Pediatr Surg,2008,43(1):79-82.
[32]GIEBLER R M,SCHERER R U,PETERS J.Incidence of neurologic complications related to thoracic epidural catheterizaton [J].Anesthesiology,1997,86(1):55-63.
[33]ELIA N,LYSAKOWSKI C,TRAMER M R.Does multimodal analgesia with acetaminophen,nonsteroidal anti-inflammatory drugs,or selective cyclooxygenase-2 inhibitors and patient-controlled analgesia morphine offer advantages over morphine alone? Meta-analyses of randomized trials [J].Anesthesiology,2005,103(6):1296-1304.
[34]MARRET E,KURDI O,ZUFFEREY P,et al.Effects of nonsteroidal anti-inflammatory drugs on patient-controlled analgesia morphine side effects:meta-analysis of randomized controlled trials [J].Anesthesiology,2005,102(6):1249-1260.
[35]LEJUS C,SURBLED M,SCHWOERER D,et al.Postoperative epidural analgesia with bupivacaine and fentanyl:hourly pain assessment in 348 paediatric cases [J].Paediatr Anaesth,2001,11(3):327-332.
[36]PETERS J W,SCHOUW R,ANAND K J,et al.Does neonatal surgery lead to increased pain sensitivity in later childhood [J].Pain,2005,114(3):444-454.
[1] 元唯安, 沈知彼, 薛利, 谭文莉, 程英武, 詹松华, 詹红生. 脊柱推拿对腰椎间盘突出症患者脑功能活动的影响[J]. 浙江大学学报(医学版), 2015, 44(2): 124-130,137.
[2] 朱丽波,张信美综述. 肥大细胞在子宫内膜异位症疼痛发生机制中的研究进展[J]. 浙江大学学报(医学版), 2013, 42(4): 461-.
[3] . 钠离子通道在神经病理性疼痛中的作用研究进展[J]. 浙江大学学报(医学版), 2011, 40(2): 217-221,229.
[4] 刘甬民,祝胜美,王奎荣,陈庆廉,郑跃英. 曲马多对切口痛诱发大鼠脊髓背角神经元c-fos基因和血液IL-6表达的抑制作用[J]. 浙江大学学报(医学版), 2009, 38(4): 292-298.