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浙江大学学报（医学版）
浙江大学学报（医学版）  1999, Vol. 28 Issue (1): 22-23    DOI: 10.3785/j.issn.1008-9292.1999.01.008
论著     
风湿性心脏病换瓣和先天性心脏病手术期间甲状腺激素的变化
金旭东, 王奎荣, 温小红
浙江医科大学附属第一医院麻醉科
Thyroid Hormone Changes in the Cardiac Valve Replacement and Congenital Heart Surgery
Jin Xudong, Wang Kuirong, Wen Xiaohong
Department of Anesthesiology, the First Affiliated Hospital. Zhejiang Medical University
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摘要：

目的:了解风湿性心脏病换瓣和先天性心脏病人心内直视手术期间甲状腺激素的变化并探讨其临床意义。方法:35例行心内直视手术病人,其中风心组19例,先心组16例,用放免法分别于诱导前、后及术毕测定T3、T4、FT3、FT4、及TSH。结果:两组病人术毕T3、FT3显着低于术前;风心组术前、术毕T3、FT3均显着低于先心组;风心组心功能Ⅳ级病人术前、术毕T3均显着低于心功能Ⅱ~Ⅲ级者。结论:我们认为,T3替代疗法主要适用于术前心功能较差的病人。
关键词： 甲状腺激素/血液;  风湿性心脏病/外科学;  先天性心脏缺损/外科学    
Abstract:

Objective:To investigate the changes of thyroid hormone levels in patients with valve replacement and congenital heart surgery. Methods:Thirty-five patients with open heart surgery were studied. Among them nineteen underwent valve replacement (V group), and sixteen received congenital heart surgery(C group).Triiodothyronine (T3),thyroxine (T4),free triiodothyronine (FT3), free thyroxine (FT4) and thyroid stimulating hormone (TSH) were measured by radioimmunoassay before and after anesthesia induction, and after operation. Results:After surgery, T3 and FT3 in two groups declined significantly. T3 and FT3 in V group were significantly lower than those in C group pre-and postoperatively. In V group, T3 in patients with cardiac function NYHA Ⅳ was significantly lower than that in patients with NYHA Ⅱ~Ⅲ before and after surgery. Conclusion:T3 as an inotropic agent after heart surgery is recommended for patients with severe cardiac dysfunction before operation.
Key words: Thyroid hormones/blood    Rheumatic disease/surg    Heart defects    congenital/surg
收稿日期: 1997-09-24 出版日期: 1999-01-25
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金旭东
王奎荣
温小红

引用本文:

金旭东, 王奎荣, 温小红. 风湿性心脏病换瓣和先天性心脏病手术期间甲状腺激素的变化[J]. 浙江大学学报（医学版）, 1999, 28(1): 22-23.

Jin Xudong, Wang Kuirong, Wen Xiaohong. Thyroid Hormone Changes in the Cardiac Valve Replacement and Congenital Heart Surgery. Journal of ZheJiang University(Medical Science), 1999, 28(1): 22-23.

链接本文:

https://www.zjujournals.com/med/CN/10.3785/j.issn.1008-9292.1999.01.008    或    https://www.zjujournals.com/med/CN/Y1999/V28/I1/22

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