对杭州市区在1986年1月1日~1989年12月31日内被诊断的245例大肠癌进行了1:1配对的病例对照研究。对所有调查因素都进行了单因素及多因素的统计分析,结果表明:饮酒史、饮自来水、慢性腹泻史、血便史及重体力活动与大肠癌有阳性联系,轻体力活动则有保护作用,以上因素均具有显着的统计学意义。
A case-control study on colorectal cancer was conducted in Hangzhou,China. The study involved 245 cases diagnosed as colorectal adenocarcinoma and the same number of populationbased controls matched by sex,age group and resident sites. The results showed that risks for colorectal cancer were significantly associated with alcohol drinking (OR 1.7 3, 9 5% CI 1.0 7~2.79), the history of chronic diarrhea (OR 5.5 5, 9 5% CI 1.4 9~2 0.7 3), bloody stools (OR 6.21, 95% CI 2.82~13.67),tap-water drinking (OR 1.03, 95% CI 1.01~1.05),and heavy physical labor (OR 1.02, 95% CI 1.00~1.04). While the only negative case associated with colorectal cancer was found to have light physical activities, (OR 0.9, 95% CI 0.80~0.98).The authors maintained that this study might provide some epidemiological basis for preventive strategies of colorectal cancer in China particularly in Hangzhou area.
国家"八五"科技攻关基金资助
周伦, 余海, 郑树. 杭州市大肠癌危险因素分析[J]. 浙江大学学报(医学版), 1996, 25(5): 204-206.
Zhou Lun, Yu Hai, Zheng Shu. RISK-FACTOR ANALYSIS OF COLORECTAL CANCER IN HANGZHOU. Journal of ZheJiang University(Medical Science), 1996, 25(5): 204-206.
https://www.zjujournals.com/med/CN/10.3785/j.issn.1008-9292.1996.05.005 或 https://www.zjujournals.com/med/CN/Y1996/V25/I5/204
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