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浙江大学学报（医学版）
浙江大学学报（医学版）  1995, Vol. 24 Issue (1): 21-23    DOI: 10.3785/j.issn.1008-9292.1995.01.007
论著     
偏头痛患者发作间歇期血6-keto-PGF1α和TXB2含量的观察
俞玉信, 谢涛, 潘以正
浙江医科大学附属第二医院神经内科
STUDY ON CONTENTS OF PLASMA 6-KETO-PGF1α ANDTXB2 IN PATIENTS WITH MIGRAINE DURING HEADACHE-FREE PERIOD
Yu Yuxing, Xie Tao, Pan Yizheng
Department of Neurology, The Second Affiliated Hospital, Zhejiang Medical University
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摘要：

通过对23例发作间歇期偏头痛患者及20名年龄、性别匹配的正常对照组血6-keto-PGF1α(6-酮前列腺素F1α)和TXB2(血栓素B2)含量的测定,发现偏头痛患者的6-keto-PGF1α含量较对照组低(P<0.01),TXB2含量则两者无差异。作者认为低水平的6-keto-PGF1α是偏头痛的发作及复发的重要物质基础之一,而TXB2则意义不大。
关键词： 偏头痛/病因学;  6-酮前列腺素F1&alpha;  /血液;  血栓素B2/血液    
Abstract:

The plasma contents of 6-keto-PGF1α,a stable metabolite of prostacyclin and TXB2,a stable metabolite of thromboxane A2 were measured in 23 patients with migraine during headache-free period and the results were compared with those of 20 normal subjects matched with age and sex.The 6-keto-PGF1αdecreased significantly in the migraine group.No difference was shown in TXB2.These data suggest that lower level of 6-keto-PGF1αis the background for its onset and recurrence but TXB2 not significant enough.
Key words: Migraine/etiol    6-ketoprostaglandin F1 alpha/blood    Thromboxane B2/blood
收稿日期: 1994-03-23 出版日期: 1995-01-25
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引用本文:

俞玉信, 谢涛, 潘以正. 偏头痛患者发作间歇期血6-keto-PGF1α和TXB2含量的观察[J]. 浙江大学学报（医学版）, 1995, 24(1): 21-23.

Yu Yuxing, Xie Tao, Pan Yizheng. STUDY ON CONTENTS OF PLASMA 6-KETO-PGF1α ANDTXB2 IN PATIENTS WITH MIGRAINE DURING HEADACHE-FREE PERIOD. Journal of ZheJiang University(Medical Science), 1995, 24(1): 21-23.

链接本文:

https://www.zjujournals.com/med/CN/10.3785/j.issn.1008-9292.1995.01.007    或    https://www.zjujournals.com/med/CN/Y1995/V24/I1/21

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