ABC immunohistochemical staining with monoclonal antibody MG7 was applied in formalinfixed and wax-embedded specimens of 74 cases of gastric carcinoma and 23 cases of cancerous transitional mucosa with intestinal metaplasia as well as 18 cases of normal gastric mucosa served as control.The rates of positivity and strong positivity were 87.84% and 78.38% respectively in cancer group,34.78% and 4.35% respectively in cancerous transitional mucosa group.The differences were statistically significant.All normal mucosa showed negative staining. The expression of MG7 was not correlated with pathological type,invasive depth and involvement of lymph nodes of gastric cancer.The degree of MG7 expression in cancer group appeared to be related to the improvement of disease prognosis,but there was no statistical significance. These results indicate that MG7 immunohistochemical staining with ABC method may be of value iii diagnosis and differential diagnosis of gastric carcinoma,its significance in prognosis needs to be further studied.
陈李华, 黄象谦, 吴琳, 黄乃侠, 黄怀德, 王开明, 彭清壁, 朱志建. 胃癌MG7抗原表达的意义及与预后的关系[J]. 浙江大学学报（医学版）, 1995, 24(1): 17-20.
Chen Lihua, Huang Xiangqian, Wu Lin, et al. SIGNIFICANCE OF GASTRIC CANCER MG_7 ANTIGEN EXPRESSION AND ITS CORRELATIONSHIP WITH PROGNOSIS. Journal of ZheJiang University(Medical Science), 1995, 24(1): 17-20.