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浙江大学学报（医学版）
浙江大学学报（医学版）  1994, Vol. 23 Issue (4): 150-152    DOI: 10.3785/j.issn.1008-9292.1994.04.003
论著     
糖尿病病人血清脂结合唾液酸含量变化与发病机理探讨
谷卫1, 宋作珪1, 周君富2
1. 浙江医科大学附属第二医院内科;
2. 浙江医科大学心脑血管病研究室
SERUM LIPID-ASSOCIATED SIALIC ACID (sLSAS) LEVELS IN DIABETICS
Gu Wei1, Song Zuo gui1, Zhou Junfu2
Second Affiliated Hospital Zhejiang Medical university
 全文: PDF(227 KB)   HTML ( ) 
摘要： 作者测定了31例糖尿病病人和50例正常人血清脂结合唾液酸(sLASA)含量,其结果分别为565.18±145.02μmol/L和439.28±118.72μmol/L,前者显著高于后者(P<0.001)。糖尿病病人(22例)住院治疗1个月后测sLASA含量显著下降,治疗前后分别为581.59±160.47和498.41±151.49μmol/L,差异非常显著(P<0.001)。在相关分析中发现血糖与sLASH含量呈正相关r=0.49(P<0.01),果糖胺与sLASA之间无相关性。31例糖尿病病人中并发症组与无并发症组的sLASA含量无差异,以上结果提示sLASA含量异常与糖尿病密切相关,并与血糖水平似相一致。
关键词： 脂结合唾液酸/血液;  糖尿病/病因学;  脂多糖类/血液    
Abstract: Serum lipid-associated sialic acid (sLASA) levels were measured in diabetic patients (n=31) and compared with those in healthy controls (n=50). The results showed that the mean sLASA level in diabetics (565.18±145.02μmol/L) was significantly higher than that in the normal controls (439.28±118.72μmol/L) (P<0.001). After one month's regular treatment, the mean sLASA level in 22 diabetics (498.41±151.49μmol/L) was significantly lower than that before treatment (581.59±160.47μmol/L) (P<0.001). Statistical analysis revealed a positive correlatinship befween fasting blood glucose (FBG) and sLASA levels (r=0.49, P<0.01). But there was no relationship between fructosamine and the sLASA level. No difference in sLASA levels was found between diabetic patients (n=31) with complications and those without.
Key words: Lipid-associated sialic acid/blood    Diabetes millitus/etiol    Lipopolysaccharides/blood
收稿日期: 1993-09-30 出版日期: 1994-07-25
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谷卫
宋作珪
周君富

引用本文:

谷卫, 宋作珪, 周君富. 糖尿病病人血清脂结合唾液酸含量变化与发病机理探讨[J]. 浙江大学学报（医学版）, 1994, 23(4): 150-152.

Gu Wei, Song Zuo gui, Zhou Junfu. SERUM LIPID-ASSOCIATED SIALIC ACID (sLSAS) LEVELS IN DIABETICS. Journal of ZheJiang University(Medical Science), 1994, 23(4): 150-152.

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https://www.zjujournals.com/med/CN/10.3785/j.issn.1008-9292.1994.04.003    或    https://www.zjujournals.com/med/CN/Y1994/V23/I4/150

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