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浙江大学学报(医学版)  1994, Vol. 23 Issue (2): 61-64    DOI: 10.3785/j.issn.1008-9292.1994.02.005
论著     
血栓性脑梗塞和脑出血脂质代谢系列对比研究
宋水江1, 黄鉴政1, 周君富2, 秦光明3
1. 浙江医科大学附属第二医院神经科;
2. 浙江医科大学附属第二医院脑血管研究室;
3. 浙江医科大学附属第二医院心血管研究室
STUDY ON LIPID METABOLISM OF ATHEROTHROMBOTIC CEREBRAL INFARCTION AND CEREBRAL HEMORRHAGE
Song Shuijiang1, Huang Jianzheng1, Zhou Junfu2, et al3
Affiliated Second Hospital, Zhejiang Medical university
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摘要: 为了揭示血栓性脑梗塞和脑出血之间脂质代谢的异同,评价脂质在脑血管疾病中的作用,本文测定了40例血栓性脑梗塞、32例脑出血和50例健康对照者血清脂类含量,结果发现血栓性脑梗塞组甘油三酯(TG)含量和脂蛋白a[Lp (a)]显著高于脑出血组和健康对照组;脑出血组总胆固醇(TC)含量显著低于对照组;而脑出血组和血栓性脑梗塞组的高密度脂蛋白胆固醇(HD-C及其亚组分(HDL2-C)含量显著低于对照组,载脂蛋白ApoB-100水平显著高于对照组。
关键词: 甘油三脂类/血液脂蛋白类/血液脱辅基脂蛋白类/血液脑梗塞/病因学脑出血/病因学    
Abstract: To show the difference in lipid metabolism between atherothrombotic cerebral infarction and cerebral hemorrhage,and evaluate the role of lipid in patients with cerebrovascular diseases, the authors measured lipid and lipoprotein concentrations in blood sample from 50 healthy controls (30 males and 20 females,mean age 56.1±5.9 years), 40 patients with atherothrombotic cerebral infarction(27 males and 13 females,mean age 65.6±9.7 years) and 32 patients with cerebral hemorrhage (25 males and 7 females, age 64.4±12.9 years). The patients with atherothrombotic infarction were found to have significantly higher levels of Lp(a), ApoB and TG and lower levels of HDL-C、HDL-2 than the control subjects; the patents with cerebral hemorrhage had significantly high levels of ApoB and lower levels of TC、HDL-C、HDL2-C than the control subjects. The LP(a), TG levels of the atherothrombotic infarction group were significantly elevated compared with those with cerebral hemorrhage.
Key words: Triglycerides/blood    Lipoproteins/blood    Apolipoproteins/blood    Cerebral infarction/etiol    Cerebral hemorrhage/etiol
收稿日期: 1993-08-30 出版日期: 1994-03-25
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宋水江
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引用本文:

宋水江, 黄鉴政, 周君富, 秦光明. 血栓性脑梗塞和脑出血脂质代谢系列对比研究[J]. 浙江大学学报(医学版), 1994, 23(2): 61-64.

Song Shuijiang, Huang Jianzheng, Zhou Junfu, et al. STUDY ON LIPID METABOLISM OF ATHEROTHROMBOTIC CEREBRAL INFARCTION AND CEREBRAL HEMORRHAGE. Journal of ZheJiang University(Medical Science), 1994, 23(2): 61-64.

链接本文:

https://www.zjujournals.com/med/CN/10.3785/j.issn.1008-9292.1994.02.005        https://www.zjujournals.com/med/CN/Y1994/V23/I2/61

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