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浙江大学学报（医学版）
浙江大学学报（医学版）  1991, Vol. 20 Issue (2): 53-56    DOI: 10.3785/j.issn.1008-9292.1991.02.002
论著     
脑脊液过氧化脂质检测及其与急性颅脑损伤关系的探讨
周君富1, 丁德云1, 陶祥洛1, 沈宏2, 胡军福2, 钟雪娟3
1. 心脑血管病研究所;
2. 附属第二医院脑外科;
3. 杭州市第三人民医院
STUDY ON THE RELATIONSHIP BETWEEN CSF-LPO AND ACUTE CRANIOCEREBRAL INJURY
Zhou Junfu1, et al
Cardio-cerebral Vascular Disease Institute
 全文: PDF(323 KB)   HTML ( ) 
摘要：

本文检测36例急性颅脑损伤患者伤后48h内CSF-LPO含量, 结果表明, 患者CSF-LPO为1.3147±0.7533μmol/L, 显著高于对照组(P<0.001);颅脑损伤程度、颅内压及颅内血肿量与CSF-LPO呈密切正相关(P<0.005~0.001);死亡组CSF-LPO为2.1540±0.3827μmol/L, 显著高于生存组(P<0.002);提示急性颅脑损伤后脂质过氧化反应剧增, CSF-LPO含量检测对判断颅脑损伤程度和评估预后有一定的参考价值。
关键词： 颅骨骨折/诊断;  脑损伤/诊断;  过氧化脂质类/脑脊髓液    
Abstract:

The lipid peroxide levels were measured in the cerebrospinal fluid (CSFLPO) of 36 cases of acute craniocerebral injury within 48 hours after accidents.The results showed that the patients'average CSF-LPO level was 1.3147±0.7533 μmol/L (X±SD), significantly higher than that of the control group (P<0.00l);the correlative coefficients of the severity of craniocerebral injury, the intracranial pressure, the size of intracranial hematoma in relation to CSF-LPO level were 0.6942, 0.7428, and 0.6483 respectively;in the non-surviving group, the CSF-LPO level was 2.1540±0.3827μmol/L, significantly higher than that of the survived group (P<0.002).
Key words: Skull fractures/diag    Brain injuries/diag    Lipid peroxides/csf
收稿日期: 1990-05-15 出版日期: 1991-03-25
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引用本文:

周君富, 丁德云, 陶祥洛, 沈宏, 胡军福, 钟雪娟. 脑脊液过氧化脂质检测及其与急性颅脑损伤关系的探讨[J]. 浙江大学学报（医学版）, 1991, 20(2): 53-56.

Zhou Junfu, et al. STUDY ON THE RELATIONSHIP BETWEEN CSF-LPO AND ACUTE CRANIOCEREBRAL INJURY. Journal of ZheJiang University(Medical Science), 1991, 20(2): 53-56.

链接本文:

https://www.zjujournals.com/med/CN/10.3785/j.issn.1008-9292.1991.02.002    或    https://www.zjujournals.com/med/CN/Y1991/V20/I2/53

[1] 傅伟明, 陶志强, 闻树群. 脑外伤患者血清髓鞘碱性蛋白测定的临床价值[J]. 浙江大学学报（医学版）, 1997, 26(5): 223-224.