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浙江大学学报(医学版)  1989, Vol. 18 Issue (2): 58-61    DOI: 10.3785/j.issn.1008-9292.1989.02.004
论著     
主动脉压力时间常数测定在冠心病诊断中的应用
韩阳, 黄元伟, 陈君柱, 方强
浙江医科大学附属第一医院内科
TIME CONSTANT OF AORTIC ARTERIAL PRESSURE IN THE DIAGNOSIS OF CORONARY ARTERY DISEASE
Han Yang, Huang Yanwei, Cheng Junzhu
Medical Department of the First Affiliated Hospital
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摘要:

本文采用改良的Simon氏法,测得14例冠心病病人的主动脉压力时间常数为1.54±0.32秒,时间常数与心动周期的比值(T)为1.91±0.28.发现时间常数和T值与核素心功能的左室射血分数(LVEF)、射血时间(ET)、充盈率(FR)呈负相关,其中与LVEF相关性最好(r=-0.831和r=-0.852),同时与左室收缩压峰值,主动脉压亦呈正相关.单纯时间常数的数值小多提示严重心肌缺血,而T值增大则提示合并有小动脉硬化所致的高血压,因此时间常数可以作为衡量左室后负荷,辅助诊断冠心病或合并高血压病的有用指标.

关键词: 冠状动脉疾病/诊断主动脉压力时间常数    
Abstract:

The time constants of aortic pressure were measured in 14 patients with coronary heart disease with an average value of 1.54±0.32 s, the T value, i. e. time constant/cardiac cycle being 1.91±0.28. Both were found to be correlated negatively with LVEF, ET and FR, positively with the peak value of systolic pressure of LV, and best correlated with LVEF (r=-0.813, r=-0.852). The low value of time constant in patients with simple coronary heart disease usually suggests serious myocardia ischemia while the high one usually indicates accompanied hypertension caused by arteriole sclerosis. Therefore, time constant can be used as a useful index both in evaluating the afterload of the left ventricle and in diagnosing coronary heart disease or hypertension.

Key words: Coronary disease/diag    Aortic pressure time constant
收稿日期: 1988-06-23 出版日期: 1989-03-25
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引用本文:

韩阳, 黄元伟, 陈君柱, 方强. 主动脉压力时间常数测定在冠心病诊断中的应用[J]. 浙江大学学报(医学版), 1989, 18(2): 58-61.

Han Yang, Huang Yanwei, Cheng Junzhu. TIME CONSTANT OF AORTIC ARTERIAL PRESSURE IN THE DIAGNOSIS OF CORONARY ARTERY DISEASE. Journal of ZheJiang University(Medical Science), 1989, 18(2): 58-61.

链接本文:

https://www.zjujournals.com/med/CN/10.3785/j.issn.1008-9292.1989.02.004        https://www.zjujournals.com/med/CN/Y1989/V18/I2/58

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