中国眼病疾病负担现状及三十年变化趋势

doi:10.3724/zdxbyxb-2021-0246

浙江大学学报（医学版）

2021, Vol. 50

Issue (4): 420-428 DOI: 10.3724/zdxbyxb-2021-0246

医学与社会

中国眼病疾病负担现状及三十年变化趋势

陈彬彬(

),楼丽霞(

),叶娟

浙江大学医学院附属第二医院眼科中心，浙江杭州 310009

Eye diseases burden in China in the past 30 years

CHEN Binbin(

),LOU Lixia(

),YE Juan

Ophthalmology Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China

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摘要：

目的：分析1990—2019年中国眼病的疾病负担状况和变化趋势。方法：利用2019年全球疾病负担研究结果，分析1990—2019年中国眼病患病人数、患病率、年龄标化患病率、伤残调整生命年（DALY）、DALY率、年龄标化DALY率及变化趋势，以及年龄标化DALY率与国家社会经济发展水平之间的相关性。结果：2019年中国人群眼病患病人数为2.1亿，年龄标化患病率为9511/10万；总DALY为472万，年龄标化DALY率为247.4/10万。疾病负担较重的眼病依次为近视力丧失、屈光性眼病和白内障，年龄标化DALY率分别为73.8/10万、70.3/10万和59.2/10万。男性患各类眼病的风险均低于女性。疾病负担较重的年龄段为50~<70岁和≥70岁。相比于1990年，2019年中国人群眼病患病数增加了134.6%，总DALY增加了113.0%。然而，总体年龄标化DALY率下降了7.5%，与国家社会经济发展水平呈明显负相关（P<0.01）。结论：在中国，近视力丧失、屈光性眼病和白内障是疾病负担较重的眼病。尽管近年来随着国家的发展，眼病年龄标化DALY率有所下降，但人口增长和老龄化导致了眼病造成的疾病负担显著上升。

关键词： 眼病; 患病率; 伤残调整生命年; 疾病负担; 人类发展指数

Abstract:

Objective: To investigate the national burden of eye diseases in China from 1990 to 2019. Methods: The national burden of eye diseases in China, including case numbers, prevalence rate, age-standardized prevalence rate (ASR), disability-adjusted life year (DALY), DALY rate and age-standardized DALY rate (ASD) were calculated and stratified by sex and age. The trends of eye diseases burden from 1990 to 2019 and the correlation between eye diseases burden and human development index (HDI) were analyzed. Results: In 2019, the total case number of eye diseases in China was 0.21 billion, the ASR was 9511/10⁵, the total number of DALY was 4.72 million, and the ASD was 247.4/10⁵. Near vision loss caused the greatest burden, followed by refraction disorders and cataract, with ASD being 73.8/10⁵, 70.3/10⁵ and 59.2/10⁵, respectively. Men had lower risks of eye diseases than women. People aged 50– <70?years old and ≥70?years old had the greatest burden of eye diseases. Compared with the year 1990, the total case number increased by 134.6% and DALY by 113.0% in 2019. The ASD of all decreased by 7.5%, and was negatively correlated with national HDI. Conclusions: Near vision loss, refraction disorders and cataract are of heavy disease burden in China. Although the ASD of eye diseases is decreased with the development of the national socioeconomic status, the eye diseases burden in China still increased with population growth and aging.

Key words: Eye disease Prevalence Disability-adjusted life year Burden of disease Human development index

收稿日期: 2021-01-29 出版日期: 2021-11-01

CLC:

R77

基金资助: 国家自然科学基金（82000948）；浙江省自然科学基金（LY17H120002）

通讯作者: 楼丽霞 E-mail: 2201015@zju.edu.cn;loulixia110@zju.edu.cn

作者简介: 陈彬彬，副主任医师，主要从事眼视光疾病临床研究；E-mail：2201015@zju.edu.cn；https：//orcid.org/0000-0001-9923-7187

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引用本文:

陈彬彬,楼丽霞,叶娟. 中国眼病疾病负担现状及三十年变化趋势[J]. 浙江大学学报（医学版）, 2021, 50(4): 420-428.

CHEN Binbin,LOU Lixia,YE Juan. Eye diseases burden in China in the past 30 years. J Zhejiang Univ (Med Sci), 2021, 50(4): 420-428.

链接本文:

http://www.zjujournals.com/med/CN/10.3724/zdxbyxb-2021-0246 或 http://www.zjujournals.com/med/CN/Y2021/V50/I4/420

表 1 1990年与2019年中国人群眼病患病数、患病率、年龄标化患病率及变化情况

图 1 1990—2019年中国人群眼病的患病数、患病率和年龄标化患病率A：患病数；B：患病率；C：年龄标化患病率.

表 2 1990年与2019年中国人群眼病引起的DALY、DALY率、年龄标化DALY率及变化情况

表 3 1990年与2019年中国不同年龄组人群眼病引起的疾病负担及变化情况

图 2 1990年至2019年中国人群眼病的DALY、DALY率和年龄标化DALY率A：DALY；B：DALY率；C：年龄标化DALY率. DALY：伤残调整生命年.

图 3 1990—2019年中国人群不同眼病的年龄标化DALY率与人类发展指数的线性回归图A：青光眼；B：白内障；C：老年性黄斑变性；D：屈光性眼病；E：近视力丧失；F：其他视力丧失. DALY：伤残调整生命年.

表 4 1990—2019年中国眼病年龄标化DALY率与人类发展指数的线性回归结果

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