Please wait a minute...
浙江大学学报(工学版)
浙江大学学报(工学版)
材料科学与化学工程     
聚合物薄膜对表面等离子体共振光谱的调制
李秋顺1,2,成荣1,张旭霖3,陈燕2,史建国2,李明宇4,于永江3,董文飞5
1. 清华大学 材料学院,北京 100084；2. 山东省科学院生物研究所,山东省生物传感器重点实验室,山东 济南250014；3. 吉林大学 电子科学与工程学院,集成光电子学国家重点联合实验室吉林大学实验区,吉林 长春130012；4. 浙江大学 现代光学仪器国家重点实验室,浙江 杭州 310027；5. 中科院生物医学检验技术重点实验室, 中国科学院苏州生物医学工程技术研究所,江苏 苏州 215163
Modulation of polymer thin films on surface plasmon #br# resonance spectroscopy
LI Qiu shun1,2, CHENG Rong1, ZHANG Xu lin 3, CHEN Yan2, SHI Jian guo2, LI Ming yu4, YU Yong jiang 3, DONG Wen fei 5
1. School of Materials Science and Engineering, Tsinghua University, Beijing 100084, China; 2. Key Biosensor Laboratory of Shandong Province, Biology Institute of Shandong Academy of Sciences, Jinan 250014, China; 3. State Key Laboratory on Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Changchun 130012, China; 4. State Key Laboratory of Modern Optical Instrumentation, Zhejiang University, Hangzhou, 310027, China; 5. CAS Key Laboratory of Bio Medical Diagnostics, Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China
 全文: PDF(3027 KB)   HTML
摘要：

为了研究聚合物薄膜结构对表面等离子体共振光谱的调制作用,以波长调制型表面等离子体共振（WISPR）分析仪为传感器件,采用层层组装法,分别在传感器芯片表面原位制备聚丙烯胺盐酸盐(PAH)/聚苯乙烯磺酸钠（PSS）及聚二烯丙基二甲基氯化铵（PDDA）/PSS多层薄膜,系统地研究在空气与水条件下这2种薄膜对共振光谱的影响,并通过理论模拟分析其内在规律.实验结果表明：对于致密的PAH/PSS薄膜,WISPR分析仪（检测范围为500~1 000 nm）所能测量的最大双层数分别为11（约70 nm,水）和45（约158 nm,空气）；每一双层PAH/PSS薄膜在水中所引起的波长移动远大于在空气中的波长移动.对于环境响应性比较强的PDDA/PSS薄膜,WISPR分析仪所能测量的最大双层数为5（约128 nm,水）,在空气中即使双层数大于40,也有共振峰出现.随着组装层数的增加,PDDA/PSS薄膜引起的共振峰在空气中交替出现,如共振峰分别在双层数4~11、19~26、29~40出现,而在双层数12~18、27~28、46~90处消失,这表明薄膜的增厚使光波导的共振模式从表面等离子体共振模式转变为横磁模的一阶模式与二阶模式.结果表明:通过调节聚合物膜的种类和结构可以有效改变表面等离子体共振光谱的共振波长及共振模式.
Abstract:

Wavelength interrogated surface plasmon resonance (WISPR) analyzer was used as sensors, and muiltlayer films of polyallylamine hydrochloride (PAH)/poly(sodium p styrenesulfonate) (PSS) and poly(diallyl  dimethylammonium chloride) (PDDA)/PSS were in situ fabricated on chips by layer by layer self assembly method, respectively, in order to understand the effect of polymer films structure on the the resonance spectra. The effects of two kinds of polymer films on the resonance spectra of WISPR analyzer in air and in water were systematically investigated. The experimental results were further explained and discussed theoretically. Experimental results showed that, for the dense PAH/PSS film, maximum of bilayer number measured by WISPR analyzer with detection range of 500~1 000 nm was 11(about 70 nm, in water) and 45(about 158 nm, in air), respectively. Wavelength shift caused by each PAH/PSS was much greater in water than that in air. As for PDDA/PSS thin films which has the relatively strong response to the environment, maximum of bilayer number was 5(about 128 nm, in water). However, resonance peaks could be observed even if n was more than 40 in air. Moreover, resonance peaks appeared and disappeared alternately with increment of bilayer number. For instance, resonance peaks could be found at 4~11, 19 ~26 and 29~40, but no peaks at 12~18, 27~28 and 46~90. This indicated that the increase in film thickness make the resonance mode of waveguide  transformed from surface plasmon resonance mode to first order mode and second order mode in transverse magnetic modes. Therefore, resonance wavelength and resonance mode can be effectively changed by adjusting the type and structure of film．
出版日期: 2015-10-15
:  O 648.14  
基金资助:

国家自然科学基金资助项目(91123029，61340032)；国家“863”高技术研究发展计划资助项目(2012AA063302，2012AA021201)；山东省自然科学基金资助项目(ZR2012CM029)；山东省自主创新及成果转化专项资助项目（2014ZZCX02602）;山东省重点研发资助项目(2015GSF117024).
通讯作者: 成荣，女，博士后.ORCID：0000 0002 5002 8170.     E-mail: chengr@tsinghua.edu.cn
作者简介: 李秋顺（1969-），男，副研究员，博士，从事光电生化分析.ODCID: 0000 0002 3612 9135. E-mail:lishun1688@126.com
服务　　
把本文推荐给朋友
加入引用管理器
E-mail Alert
RSS
作者相关文章　　

引用本文:

李秋顺,成荣,张旭霖,陈燕,史建国,李明宇,于永江,董文飞. 聚合物薄膜对表面等离子体共振光谱的调制[J]. 浙江大学学报(工学版), 10.3785/j.issn.1008 973X.2015.09.025.

LI Qiu shun, CHENG Rong, ZHANG Xu lin, CHEN Yan, SHI Jian guo, LI Ming yu, YU Yong jiang,DONG Wen fei. Modulation of polymer thin films on surface plasmon #br# resonance spectroscopy. JOURNAL OF ZHEJIANG UNIVERSITY (ENGINEERING SCIENCE), 10.3785/j.issn.1008 973X.2015.09.025.

链接本文:

http://www.zjujournals.com/eng/CN/10.3785/j.issn.1008 973X.2015.09.025    或    http://www.zjujournals.com/eng/CN/Y2015/V49/I9/1796

［1］ 王二伟, 鱼卫星, 王成, 等. 用表面等离子体共振传感器检测纳米间距［J］. 中国光学, 2013, 6(2): 259-266．
WANG Er wei,YU Wei xing,WANG Cheng,et al. Nanogap measurement by using surface plasmon resonance sensor ［J］.Chinese Optics,2013,6(2)： 259-266．
［2］ 刘霞, 李蓉卓, 李蕾, 等. 纳米金标记抗体增强 SPR 检测大肠杆菌 O157: H7 的研究［J］. 高等学校化学学报, 2013, 34(6): 1333-1338．
LIU Xia,LI Rong zhuo,LI Lei,et al.Immuno analysis of E. coli O157:H7 based on Au nanoparticles labelling antibody using SPR biosensor ［J］.Chemical Journal of Chinese Universities,2013,34(6)： 1333-1338．
［3］ CHINOWSKY T M,SOELBERG S D,BAKER P,et al. Portable 24 analyte surface plasmon resonance instruments for rapid,versatile biodetection ［J］. Biosensors and Bioelectronics,2007, 22(9): 2268-2275．
［4］ LI Q, HE H, WANG J, et al. Label free detection of biotin using nanoporous TiO2/DNA thin film coated wavelength interrogated surface plasmon resonance sensors ［J］. Chemical Research in Chinese Universities,2014, 30(1): 157-162．
［5］ 张喆, 祁志美. TiO2纳米多孔薄膜漏模光波导共振传感器研究小分子的光谱灵敏度［J］. 分析化学, 2010, 38(11): 1538-1543．
ZHANG Zhe,QI Zhi mei.Study of spectral sensitivity to small molecule analytes using TiO2 nanoporous thin film leaky waveguide resonance sensors ［J］.Chinese Journal of Analytical Chemistry,2010,38(11)：1538-1543．
［6］ ZHANG Z, LU D F, QI Z M. Application of porous TiO2 thin films as wavelength interrogated waveguide resonance sensors for bio/chemical detection ［J］. The Journal of Physical Chemistry C, 2012, 116(5): 3342-3348．
［7］ GAO C,LEPORATTI S,MOYA S,et al. Swelling and shrinking of polyelectrolyte microcapsules in response to changes in temperature and ionic strength ［J］. Chemistry A European Journal, 2003, 9(4): 915-920．
［8］ LI Q S, ZHANG X L, HE H, et al. Improved detecting sensitivity of long period fiber gratings by polyelectrolyte multilayers: the effect of film structures ［J］. Optics Communications, 2014, 331(22): 39-44．
［9］ DONG W,FERRI J K,ADALSTEINSSON T,et al. Influence of shell structure on stability, integrity and mesh size of polyelectrolyte capsules: mechanism and strategy for improved preparation ［J］. Chemistry of Materials, 2005, 17(10): 2603-2611．
［10］ ZHANG Z,LU D,LIU Q, et al. Wavelength interrogated surface plasmon resonance sensor with mesoporous silica film enhanced sensitivity to small molecules ［J］. Analyst, 2012, 137(20): 4822-4828．
［11］ LI Q, ZHANG X L, YU Y S, et al. Enhanced sucrose sensing sensitivity of long period fiber grating by self assembled polyelectrolyte multilayers ［J］. Reactive and Functional Polymers, 2011, 71(3): 335-339．
［12］ ITURRI RAMOS J J, STAHLS, RICHTER R P, et al. Water content and buildup of poly (diallyldimethylammonium chloride)/poly (sodium 4 styrenesulfonate) and poly (allylamine hydrochloride)/poly (sodium 4 styrenesulfonate) polyelectrolyte multilayers studied by an in situ combination of a quartz crystal microbalance with dissipation monitoring and spectroscopic ellipsometry ［J］. Macromolecules, 2010, 43(21): 9063-9070．
［13］ GUZMN E,RITACCO H,RUBIO J E, et al. Salt induced changes in the growth of polyelectrolyte layers of poly (diallyl dimethylammonium chloride) and poly (4 styrene sulfonate of sodium) ［J］. Soft Matter, 2009, 5(10): 2130-2142．
［14］ DRR M,MENGES B,KNOLL W, et al. Direct measurement of increased light intensity in optical waveguides coupled to a surface plasmon spectroscopy setup ［J］. Applied Physics Letters, 2007, 91(2): 21-113．
［15］ MILLER M D,BRUENING M L. Correlation of the swelling and permeability of polyelectrolyte multilayer films ［J］. Chemistry of Materials, 2005, 17(21): 5375-5381．
［16］ KOLARIK L,FURLONG D N,JOY H, et al. Building assemblies from high molecular weight polyelectrolytes ［J］. Langmuir, 1999, 15(23): 8265-8275．
［17］ YU Y,ZHOU Y,LI Q, et al. In situ molecular self assembly and sensitive label free detection of streptavidin via a wavelength interrogated surface plasmon resonance sensor ［J］. Chemical Research in Chinese Universities, 2013, 29(6): 1219-1224．
［18］ 于永江, 魏光耀, 周颖, 等. 基于 DNA 和聚阳离子的层层组装型大孔薄膜: 聚电解质结构及盐浓度对孔结构的影响［J］. 高等学校化学学报, 2013, 34(11): 2644-2649．
YU Yong jiang,WEI Guang yao,ZHOU Ying,et al.Self assembled DNA/polycations macroporous multilayer thin films： the effect of polyelectrolyte structure and salt concentration on the porous architectur ［J］.Chemical Journal of Chinese Universities,2013,34(11)：2644-2649．
［19］ YANG R,DONG W,MENG X, et al. Nanoporous TiO2/polyion thin film coated long period grating sensors for the direct measurement of low molecular weight analytes ［J］. Langmuir, 2012, 28(23): 8814-8821．
［20］ VILLAR I D,MATIAS I,ARREGUI F, et al. Analysis of one dimensional photonic band gap structures with a liquid crystal defect towards development of fiber optic tunable wavelength filters ［J］. Optics Express, 2003, 11(5): 430-436．
［21］ VILLAR I D,MATIAS I R,ARREGUI F J, et al. Optimization of sensitivity in long period fiber gratings with overlay deposition ［J］. Optics Express, 2005, 13(1): 56-69．
［22］ 李明宇,刘旭,张锦龙,等.薄膜法布里 珀罗滤光片中反射高斯光束分裂现象［J］.物理学报,2007,56(3)：1746-1750．
LI Ming yu,LIU Xu,ZHANG Jin long,et al. Reflected Gaussian beam splitting phenomenon in the thin film Fabry Perot filter ［J］.Acta Physica Sinica,2007,56(3)：1746-1750．
［23］ LI M,LIU X,ZHANG J,et al.Rigorous analysis of the spatial dispersion effect in multilayer thin film coatings ［J］.Journal of the Optical Society of America A,2007,24(8)：2328-2333．
［24］ MACLEOD H A.Thin film optical filters ［M］. Bristol:Institute of Physics Publishin,2002．
［25］ 唐晋发,顾培夫.薄膜光学与技术 ［M］.北京：机械工业出版社,1989.
No related articles found!