| Articles |
|
|
|
|
| Evaluation of the safety and efficacy of transcatheter aortic valve implantation in patients with a severe stenotic bicuspid aortic valve in a Chinese population |
| Xian-bao Liu, Ju-bo Jiang, Qi-jing Zhou, Zhao-xia Pu, Wei He, Ai-qiang Dong, Yan Feng, Jun Jiang, Yong Sun, Mei-xiang Xiang, Yu-xin He, You-qi Fan, Liang Dong, Jian-an Wang |
| Cardiovascular Key Lab of Zhejiang Province, Department of Cardiology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China; Department of Radiology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China; Department of Echocardiography, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China; Department of Anesthesiology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China; Department of Cardiosurgery, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China |
|
|
|
Abstract Objective: The purpose of this study is to evaluate the safety and efficacy of transcatheter aortic valve implantation (TAVI) in patients with a severe stenotic bicuspid aortic valve (BAV) in a Chinese population. While several groups have reported the feasibility, efficacy, and safety of TAVI for patients with a BAV, worldwide experience of the technique is still limited, especially in China. Methods: From March 2013 to November 2014, high surgical risk or inoperable patients with symptomatic severe aortic stenosis (AS) who had undergone TAVI at our institution were selected for inclusion in our study. Results were compared between a BAV group and a tricuspid aortic valve (TAV) group. Results: Forty patients were included in this study, 15 (37.5%) of whom were identified as having a BAV. In the BAV group, the aortic valve area was smaller ((0.47卤0.13) vs. (0.59卤0.14) cm2), the ascending aortic diameter was larger ((40.4卤4.4) vs. (36.4卤4.3) mm), and the concomitant aortic regurgitation was lower. No significant differences were found between the groups in the other baseline characteristics. No differences were observed either in the choice of access or valve size. The procedural success achieved in this study was 100%. There were no differences between groups in device success (86.7% vs. 88.0%), 30-d mortality (6.7% vs. 8.0%), or 30-d combined end point (13.3% vs. 12.0%). The incidences of new pacemaker implantation, paravalvular regurgitation and other complications, recovery of left ventricle ejection fraction and heart function were similar in both groups. Conclusions: Patients with a severely stenotic BAV can be treated with TAVI, and their condition after treatment should be similar to that of people with a TAV.
|
|
Received: 21 January 2015
Published: 05 March 2015
|
|
|
|
Cite this article:
Xian-bao Liu, Ju-bo Jiang, Qi-jing Zhou, Zhao-xia Pu, Wei He, Ai-qiang Dong, Yan Feng, Jun Jiang, Yong Sun, Mei-xiang Xiang, Yu-xin He, You-qi Fan, Liang Dong, Jian-an Wang. Evaluation of the safety and efficacy of transcatheter aortic valve implantation in patients with a severe stenotic bicuspid aortic valve in a Chinese population. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2015, 16(3): 208-214.
URL:
http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.B1500017 OR http://www.zjujournals.com/xueshu/zjus-b/Y2015/V16/I3/208
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
| |
Shared |
|
|
|
|
| |
Discussed |
|
|
|
|
