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Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)  2014, Vol. 15 Issue (8): 750-755    DOI: 10.1631/jzus.B1400081
Case Reports     
Heterochronic bilateral ectopic pregnancy after ovulation induction
Bo Zhu, Gu-feng Xu, Yi-feng Liu, Fan Qu, Wei-miao Yao, Yi-min Zhu, Hui-juan Gao, Dan Zhang
Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China; Key Laboratory of Reproductive Genetics, Ministry of Education, Zhejiang University, Hangzhou 310006, China
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Abstract  Ectopic pregnancy is identified with the widely-applied assisted reproductive technology (ART). Bilateral ectopic pregnancy is a rare form of ectopic pregnancy which is difficult to be diagnosed at the pre-operation stage. In this paper, we presented an unusual case of heterochronic bilateral ectopic pregnancy after stimulated intrauterine insemination (IUI), where there has been a delay of 22 d between the diagnoses of the two ectopic pregnancies. Literature was reviewed on the occurrence of bilateral ectopic pregnancy during the past four years in the MEDLINE database. We found 16 cases of bilateral ectopic pregnancy reported since 2008, and analyzed the characteristics of those cases of bilateral ectopic pregnancy. We emphasize that ovulation induction and other ARTs may increase the risk of bilateral ectopic pregnancy. Because of the difficulty in identification of bilateral ectopic pregnancy by ultrasonography, the clinician should be aware that the treatment of one ectopic pregnancy does not preclude the occurrence of a second ectopic pregnancy in the same patient and should pay attention to the intra-operation inspection of both side fallopian tubes in any ectopic pregnancy case.

Key wordsHeterochronic bilateral ectopic pregnancy      Assisted reproductive technology      Intrauterine insemination      Ovulation induction     
Received: 18 March 2014      Published: 05 August 2014
CLC:  R711.76  
Cite this article:

Bo Zhu, Gu-feng Xu, Yi-feng Liu, Fan Qu, Wei-miao Yao, Yi-min Zhu, Hui-juan Gao, Dan Zhang. Heterochronic bilateral ectopic pregnancy after ovulation induction. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2014, 15(8): 750-755.

URL:

http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.B1400081     OR     http://www.zjujournals.com/xueshu/zjus-b/Y2014/V15/I8/750

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