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| Allelic frequency distributions of 21 non-combined DNA index system STR loci in a Russian ethnic minority group from Inner Mongolia, China |
| Hong-dan Wang, Chun-mei Shen, Wen-juan Liu, Yu-dang Zhang, Guang Yang, Jiang-wei Yan, Hai-xia Qin, Bo-feng Zhu |
| School of Medicine, Xi'an Jiaotong University, Xi'an 710061, China; People's Hospital of Zhengzhou University, Zhengzhou 450003, China; Medical Genetic Institute of Henan Province, People's Hospital of Henan Province, Zhengzhou 450003, China; Blood Center of Shaanxi Province, Xi'an 710061, China; Vascular Biology Center, Georgia Health Sciences University, Augusta, GA 30912, USA; Beijing Institute of Genomics, Chinese Academy of Science, Beijing 100029, China; Department of Internal Medicine, Morehouse School of Medicine, Atlanta, GA 30303, USA |
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Abstract We studied the allelic frequency distributions and statistical forensic parameters of 21 new short tandem repeat (STR) loci and the amelogenin locus, which are not included in the combined DNA index system (CODIS), in a Russian ethnic minority group from the Inner Mongolia Autonomous Region, China. A total of 114 bloodstain samples from unrelated individuals were extracted and co-amplified with four fluorescence-labeled primers in a multiplex polymerase chain reaction (PCR) system. Using capillary electrophoresis, the PCR products of the 21 STR loci were separated and genotyped. A total of 161 alleles were observed in the Russian ethnic minority group, and corresponding allelic frequencies ranged from 0.0044 to 0.5965. The 21 non-CODIS STR loci of the Russian ethnic minority group were characterized by high genetic diversity and therefore may be useful for elucidating the population’s genetic background, for individual identification, and for paternity testing in forensic practice.
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Received: 25 September 2012
Published: 04 June 2013
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Cite this article:
Hong-dan Wang, Chun-mei Shen, Wen-juan Liu, Yu-dang Zhang, Guang Yang, Jiang-wei Yan, Hai-xia Qin, Bo-feng Zhu. Allelic frequency distributions of 21 non-combined DNA index system STR loci in a Russian ethnic minority group from Inner Mongolia, China. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2013, 14(6): 533-540.
URL:
http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.B1200262 OR http://www.zjujournals.com/xueshu/zjus-b/Y2013/V14/I6/533
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