| Biomedicine |
|
|
|
|
| Lance-Adams syndrome: a report of two cases |
| ZHANG Yan-xing, LIU Jian-ren, JIANG biao, LIU Hui-qin, DING Mei-ping, SONG Shui-jiang, ZHANG Bao-rong, ZHANG Hong, XU Bin, CHEN Huai-hong, WANG Zhong-jin, HUANG Jian-zheng |
| Department of Neurology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China; Department of Neurology, Shaoxing People’s Hospital, Shaoxing 312000, China; Department of Radiology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China; Department of Nuclear Medicine, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China; Department of Neurology, the Second Affiliated Hospital, Zhejiang University of Traditional Chinese Medicine, Hangzhou 310005, China; Department of Geratology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China |
|
|
|
Abstract Chronic post-hypoxic myoclonus, also known as Lance-Adams syndrome (LAS), is a rare complication of successful cardiopulmanry resuscitation often accompanied by action myoclonus and cerebellar ataxia. It is seen in patients who have undergone a cardiorespiratory arrest, regained consciousness afterwards, and then developed myoclonus days or weeks after the event. Worldwide, 122 cases have been reported in the literature so far, including 1 case of Chinese. Here we report 2 Chinese LAS patients with detailed neuroimagings. Cranial single photon emission computed tomography (SPECT) of patient 1, a 52-year-old woman, showed a mild hypoperfusion in her left temporal lobe, whereas patient 2, a 54-year-old woman, manifested a mild bilateral decrease of glucose metabolism in the frontal lobes and a mild to moderate decrease of the N-acetyl aspartate (NAA) peak in the bilateral hippocampi by cranial [18F]-fluorodeoxyglucose positron emission tomographic (PET) scan and cranial magnetic resonance spectroscopy (MRS), respectively. We also review the literature on the neuroimaging, pathogenesis, and treatment of LAS.
|
|
Received: 24 June 2007
|
|
|
|
Cite this article:
ZHANG Yan-xing, LIU Jian-ren, JIANG biao, LIU Hui-qin, DING Mei-ping, SONG Shui-jiang, ZHANG Bao-rong, ZHANG Hong, XU Bin, CHEN Huai-hong, WANG Zhong-jin, HUANG Jian-zheng. Lance-Adams syndrome: a report of two cases. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2007, 8(10): 715-720.
URL:
http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.2007.B0715 OR http://www.zjujournals.com/xueshu/zjus-b/Y2007/V8/I10/715
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
| |
Shared |
|
|
|
|
| |
Discussed |
|
|
|
|
