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ZJUS-B
Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology)  2007, Vol. 8 Issue (1): 60-69    DOI: 10.1631/jzus.2007.B0060
Biomedicine     
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS): the mechanism, present strategies and future perspectives of therapies
LUH Shi-ping, CHIANG Chi-huei
Department of Surgery, Chung-Shan Medical University Hospital, 402 Taichung, Taiwan, China; Division of Pulmonary Immunology and Infectious Diseases, Taipei Veterans General Hospital, 112 Taipei, Taiwan, China
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Abstract  Acute lung injury/acute respiratory distress syndrome (ALI/ARDS), which manifests as non-cardiogenic pulmonary edema, respiratory distress and hypoxemia, could be resulted from various processes that directly or indirectly injure the lung. Extensive investigations in experimental models and humans with ALI/ARDS have revealed many molecular mechanisms that offer therapeutic opportunities for cell or gene therapy. Herein the present strategies and future perspectives of the treatment for ALI/ARDS, include the ventilatory, pharmacological, as well as cell therapies.

Key words： Acute lung injury      Acute respiratory distress syndrome      Ventilator      Cell therapy     
Received: 26 July 2006     
CLC:  R56  
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LUH Shi-ping
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LUH Shi-ping, CHIANG Chi-huei. Acute lung injury/acute respiratory distress syndrome (ALI/ARDS): the mechanism, present strategies and future perspectives of therapies. Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2007, 8(1): 60-69.

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http://www.zjujournals.com/xueshu/zjus-b/10.1631/jzus.2007.B0060     OR     http://www.zjujournals.com/xueshu/zjus-b/Y2007/V8/I1/60

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