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Distributed heterogeneous inspecting system and its middleware-based solution
HUANG Li-can, WU Zhao-hui, PAN Yun-he
Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering), 2003, 4(5): 542-548.
https://doi.org/10.1631/jzus.2003.0542
There are many cases when an organization needs to monitor the data and operations of its supervised departments, especially those departments which are not owned by this organization and are managed by their own information systems. Distributed Heterogeneous Inspecting System (DHIS) is the system an organization uses to monitor its supervised departments by inspecting their information systems. In DHIS, the inspected systems are generally distributed, heterogeneous, and constructed by different companies. DHIS has three key processes-abstracting core data sets and core operation sets, collecting these sets, and inspecting these collected sets. In this paper, we present the concept and mathematical definition of DHIS, a metadata method for solving the interoperability, a security strategy for data transferring, and a middleware-based solution of DHIS. We also describe an example of the inspecting system at WENZHOU custom.
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Distributed certification application via a trusted dealer
LIU Duan-yang, PAN Xue-zeng, PING Ling-di
Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering), 2003, 4(5): 555-559.
https://doi.org/10.1631/jzus.2003.0555
Distributed certification via threshold cryptography is much more secure than other ways to protect certification authority (CA)\'s private key, and can tolerate some intrusions. As the original system such as ITTC, etc., is unsafe, inefficient and impracitcal in actual network environment, this paper brings up a new distributed certification scheme, which although it generates key shares concentratively, it updates key shares distributedly, and so, avoids single-point failure like ITTC. It not only enhances robustness with Feldman verification and SSL protocol, but can also change the threshold (t,k) flexibly and robustly, and so, is much more practical. In this work, the authors implement the prototype system of the new scheme and test and analyze its performance.
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Application of uncertainty reasoning based on cloud model in time series prediction
ZHANG Jin-chun, HU Gu-yu
Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering), 2003, 4(5): 578-583.
https://doi.org/10.1631/jzus.2003.0578
Time series prediction has been successfully used in several application areas, such as meteorological forecasting, market prediction, network traffic forecasting, etc., and a number of techniques have been developed for modeling and predicting time series. In the traditional exponential smoothing method, a fixed weight is assigned to data history, and the trend changes of time series are ignored. In this paper, an uncertainty reasoning method, based on cloud model, is employed in time series prediction, which uses cloud logic controller to adjust the smoothing coefficient of the simple exponential smoothing method dynamically to fit the current trend of the time series. The validity of this solution was proved by experiments on various data sets.
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Quality of life and cost-effectiveness of combined therapy for reflux esophagitis
SI Jian-min, WANG Liang-jing, CHEN Shu-jie, ZHAO Lan, DAI Ning
Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering), 2003, 4(5): 602-606.
https://doi.org/10.1631/jzus.2003.0602
Objective: To evaluate clinical, Quality of Life (QoL) and medical cost outcomes in patients with symptomatic reflux esophagitis (RE) receiving different \"triple combination therapy\". Methods: A multicenter medical effectiveness trial conducted in 10 hospitals of 5 regions in Zhejiang Province. 248 patient-volunteers were assigned to 8 weeks of \"triple combination therapy\" with Lansoprazole plus Cisapride and Sucralfate or Ranitidine plus Cisapride and Sucralfate. Main outcomes assessment included symptoms scale scores, RE severity, QoL at baseline and 8 weeks. Medical cost data were collected with cost analysis questionnaire. Results: (1) More Lansoprazole group patients noted RE symptoms resolution than Ranitidine group (92.3% vs 78.4%, P<0.01). There was no striking difference between two groups in RE healing rate (90.8% vs 82.9%, P>0.05). (2) RE significantly impaired QoL of patients (P<0.001).Compared with Ranitidine group, QoL in Lansoprazole group had significant improvement (rate of \"good\" QoL 64.5% vs 45.6%, P<0.01). (3)There was close correlation between symptomic effectiveness and QoL rating scale in both the Lansoprazole and Ranitidine group (P<0.01, r=0.235 and 0.353 respectively). There were no statistical difference of medical cost between the two groups (P>0.05). Conclusion: RE significantly impaired QoL of patients. \"Triple combination therapies\" can significantly improve RE symptoms and QoL. Lansoprazole combination therapy was more cost-effective than Ranitidine combination group.
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Anticoagulation therapy in intra-aortic balloon counterpulsation: Does IABP really need anti-coagulation?
JIANG Chen-yang, ZHAO Li-li, WANG Jian-an, SAN Jiang, MOHAMMOD Balgaith
Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering), 2003, 4(5): 607-611.
https://doi.org/10.1631/jzus.2003.0607
Objective: To investigate if intra-aortic balloon pump (IABP) is contraindicated without anticoagulation therapy. Methods: Some 153 IABP patients in the King Abdulaziz Cardiac Center (KSA) were randomly assigned into two groups. Anticoagulation group (Group A) consisted of 71 patients who were given heparin intravenously with target aPTT 50-70 seconds. Non-anticoagulation group (Group B) consisted of 82 patients without intravenous heparin during balloon pumping. Hematological parameters including platelet count, D-dimer, Plasminogen activator inhibitor-1 (PAI-1) and fibrinogen degradation products (FDP) were checked respectively at the point of baseline, 24 hours, 48 hours and 24 hours post IABP counterpulsation. Clot deposits on balloon surface, vascular complications from IABP including bleeding and limb ischemia were recorded. Results: Platelet count and PAI-1 level decreased at 24 hours and 48 hours in both groups (P<0.05). D-dimer and FDP level increased at 24 hours and 48 hours in both groups (P<0.05), but returned to the baseline level 24 hours post IABP removal (P>0.05). Three patients in Group A and 2 patients in Group B developed minor limb ischemia(P>0.05). No major limb ischemia in either group. Two patients in Group A suffered major bleeding and required blood transfusion or surgical intervention, whereas no patient had major bleeding in Group B. Eight patients had minor bleeding in Group A, but only 2 patients in Group B (P<0.05). No clot deposit developed on IABP surface in either group. Conclusion: IABP is safe without routine anticoagulation therapy. Selecting appropriate artery approach and early detection intervention are key methods for preventing complications.
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Effects of atorvastatin on vascular remodeling in spontaneously hypertensive rats
GE Chang-jiang, HU Shen-jiang, WU Yao-sen, CHEN Nai-yun
Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering), 2003, 4(5): 612-615.
https://doi.org/10.1631/jzus.2003.0612
Objective: To investigate the structural changes of aorta, and evaluate the effects of atorvastatin on the remodeling of thoracic aorta in spontaneously hypertensive rats (SHR). Methods: Twelve eight-week-old SHR were randomized into atorvastatin treated group (ATV group, n=6) and distilled water group (DW group, n=6); Wistar-Kyoto rats (WKY) were used as normal controls. Atorvastatin was administered to ATV group for 10 weeks by gavage in mixture with distilled water (1 ml); the latter two groups were given the same amount of distilled water by gavage for 10 weeks. Systolic blood pressure of caudal artery was examined before and after treatment, and serum concentrations of total cholesterol, triglycerides and HDL-C were measured. Wall thickness, media thickness, medial cross-sectional area and lumen diameter of thoracic aorta were assessed with computed video processing. Results: Systolic blood pressure in ATV group was markedly lower than that in DW group (P<0.01). Compared with DW group and WKY group, serum concentrations of total cholesterol, triglycerides and HDL-C in ATV group were significantly lower (P<0.01, P<0.05). Wall thickness, media thickness, and medial cross-sectional area to lumen ratio in DW group were significantly higher than those in WKY group and ATV group (P<0.01,P<0.05), but no such difference was found between WKY group and ATV group (P>0.05). Conclusion: Vascular structural changes of aorta are due to the alteration of the vessel wall in early stage of SHR. Atorvastatin can markedly improve vascular remodeling.
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Antiphospholipid syndrome:a survey of clinical characters in ten cases
CHEN Li-hua, JIANG Ling-ling, LI You-ming, PENG Qing-bi
Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering), 2003, 4(5): 616-619.
https://doi.org/10.1631/jzus.2003.0616
Objective: To gain further understanding of the antiphospholipid syndrome (APS). Methods: Analysing clinical and laboratory data on ten cases of APS. Results: Thrombocytopenia appeared in all cases. Venous thrombi of limbs appeared in five cases and neurological abnormalities in two cases. Renal impairments were found in three cases. One case manifested left renal venous thrombi and the other two cases thrombotic microangiopathy. Budd-Chiari syndrome was found in one case. One of the ten cases was catastrophic APS (CAPS) presented as acute diffuse swelling, cyanosis, pain, ischemia and necrosis in fingers and limbs, recurrent shock, ascites, hepatic and respiratory dysfunction. Anticoagulants and corticosteroids could be effective for dealing with APS. It was critical to treat catastrophic APS with anticoagulants or plasmapheresis as early as possible. Conclusions: APS shows variable manifestations for good prognosis, but catastrophic APS has fatal risk. The main treatment for APS is the use of anticoagulants and immunosuppressives.
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Relationship between cholecystolithiasis and polypoid gallbladder
WU Ai-jiao, LI Ying-qi, DU Li-an
Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering), 2003, 4(5): 620-622.
https://doi.org/10.1631/jzus.2003.0620
Objective: To study the relationship between cholecystolithiasis and polypoid gallbladder(PLG), 260 patients with polypoid gallbladder were investigated. The patients were divided into 2 groups: group A (PLG combined with cholecystolithiasis) and group B (without cholecystolithiasis). The clinical pathological characteristics were analyzed. The intestinal epithelium metaplasia and atypical hyperplasia of the gallbladder mucosa were observed under light microscope. Results: Intestinal epithelium metaplasia and atypical hyperplasia of gallbladder mucosa were found in 47 of the 260 cases. The pathological lesions included 16 gallbladder carcinoma, 11 adenomatosis polyp, 5 myoadenoma, 7 cholesterol polyp, 4 inflammatory polyp and 4 adenomatosis hyperplasia, which occurred in 26 and 21 patients in group A and group B, i.e. 44.0% and 10.3% respectively. The difference between group A and group B was statistically significant (P<0.01). Conclusion: Cholecystolithiasis and the succeeding inflammatory reaction is a risk-factor for the polypoid gallbladder to develop tumour.
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21 articles
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