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ZJUS-A
Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering)  2000, Vol. 1 Issue (2): 190-195    DOI: 10.1631/jzus.2000.0190
Science & Engineering     
HEPATIC GLUTATHIONE S-TRANSFETASE ACTIVITY IN MOSQUITOFISH (GAMBUSIA AFFINIS) AND TOPMOUTH GUDGEON (PSEUDORASOBORA PARVA) EXPOSED TO FENITROTHION
Sorsa Sota Solomon, FAN De-fang, LI Shao-nan
Institute of Pesticide Environmental Toxicology, Department of Plant Protection, Huajiachi Campus of Zhejiang University, Hangzhou 310029, China
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Abstract  Two common fish species, mosquitofish (Gambusia affinis) and topmouth gudgeon (Pseudorasobora parva ) were exposed to different concentrations of fenitrothion in static system for 96 h. Hepatic glutathione S-transferase activity was evaluated after 48 and 96 h pesticide exposure, and was also examined in fish pretreated with pepironyl butoxide and triphenyl phosphate and then exposed to fenitrothion. Results indicated presence of intense glutathione S-transferase activity in both species, mosquitofish exhibiting the higher activity. In both species the activity decreased as the concentration of fenitrothion increased, topmouth gudgeon being more susceptible than mosquitofish. In mosquitofish pretreated with pepironyl butoxide, glutathione S-transferase activity was increased (11.8%) comparded with the control but in topmouth gudgeon it was decreased (21.6%) at the end of 96 h. Glutathione S-transferase activity was significantly reduce in both species pretreated with triphenyl phosphate at the end of 96 h exposure, topmouth gudgeon being highly susceptible.

Key words： fenitrothion      hepatic GST activity      glutathione S-transferase      fish     
Received: 20 May 1999     
CLC:  X503  
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Sorsa Sota Solomon
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Sorsa Sota Solomon, FAN De-fang, LI Shao-nan. HEPATIC GLUTATHIONE S-TRANSFETASE ACTIVITY IN MOSQUITOFISH (GAMBUSIA AFFINIS) AND TOPMOUTH GUDGEON (PSEUDORASOBORA PARVA) EXPOSED TO FENITROTHION. Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering), 2000, 1(2): 190-195.

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http://www.zjujournals.com/xueshu/zjus-a/10.1631/jzus.2000.0190     OR     http://www.zjujournals.com/xueshu/zjus-a/Y2000/V1/I2/190

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