| Bioscience & Biotechnology |
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| A large scale screen for genes (3rd chromosome) related to Wingless signaling pathway |
| LIN Xin-da, LIN Xin-hua, CHENG Jia-an |
| Institute of Applied Entomology, Zhejiang University, Hangzhou 310029, China; Division of Developmental Biology, Cincinnati Children\'s Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229, USA |
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Abstract A wing specific F1 genetic screen was carried out using the powerfulDrosophila genetic system, combined with yeast FRT/FLP and GAL4/UAS system. Form the wing phenotypes and germline clone embryonic cuticle phenotypes observed in these mutant alleles, a number of mutant alleles of known or unknown genes were isolated. Among them, fifteen mutant alleles related to Wingless signal transduction were further isolated; the arm of these mutations located were determined, and their location in the chromosome were roughly mapped.
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Received: 04 March 2003
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