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ZJUS-A
Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering)  2000, Vol. 1 Issue (2): 227-228    DOI: 10.1631/jzus.2000.0227
Medicine     
THE RELATIONSHIP BETWEEN ULCER RECURRENCE AND HELICOBACTER PYLORI: A PROSPECTIVE ONE-YEAR FOLLOW-UP STUDY IN CHINA
SI Jian-min, JIN Yi-yi, WU Jia-guo
Sir Run Run Shaw Hospital, Medical College of Zhejiang University, Hangzhou 310016, China; Department of Gastroenterology, People\'s Hospital of Zhejiang Province,Hangzhou 310014
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Abstract  To study the relationship between ulcer recurrence and Helicobacter Pylori. 147 patients with peptic ulcer were divided into H. Pylori infected group and H.pylori uninfected group by rapid urease test, serum antibody examination and histopathology of gastric biopsy specimens. We assigned all patients to receive dual oral therapy with omeprazole 40 mg/day for 4 weeks and amoxicillin 2000 mg/day for 2 weeks. To all patients, repeated gastroscope was performed at 8 weeks and one-year after beginning therapy to record whether the ulcer was cured. Endoscopic biopsy was also performed to dertermine H.pylori status. One year later, H.pylori positive patients had a higher ulcer recurrent rate than H.pylori negative patients(23.33% vs 2.70%; P=0.001). Ulcer recurrence was closely related to H.pylori infection. H.pylori was the risk factor for ulcer relapse.

Key words： H. pylori reinfection      peptic ulcer/relapse     
Received: 28 May 1999     
CLC:  R69  
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SI Jian-min
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SI Jian-min, JIN Yi-yi, WU Jia-guo. THE RELATIONSHIP BETWEEN ULCER RECURRENCE AND HELICOBACTER PYLORI: A PROSPECTIVE ONE-YEAR FOLLOW-UP STUDY IN CHINA. Journal of Zhejiang University-SCIENCE A (Applied Physics & Engineering), 2000, 1(2): 227-228.

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http://www.zjujournals.com/xueshu/zjus-a/10.1631/jzus.2000.0227     OR     http://www.zjujournals.com/xueshu/zjus-a/Y2000/V1/I2/227

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