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浙江大学学报（理学版）
浙江大学学报（理学版）
生命科学     
新生儿败血症休克血浆内皮素水平的研究
杨仁志　　　 (杭州大学医院　杭州 310028)　 冯建华　　　(浙江医科大学附属儿童医院　杭州 310003)
Studies on the Plasma Endothelin in Newborn Babies with Septic Shock
Yang Renzhi (Hangzhou University Hospital, Hangzhou 310028) Feng Jianhua ( Children ' s Hospital of Zhejiang Medical University, Hangzhou 310010)
 全文: PDF(148 KB)  
摘要： 本文应用放免法测定了 40例败血症休克新生儿血浆 ET 水平.结果表明: ( 1)新生儿败血症休克组 血浆 ET 水平明显高于对照组,重度休克高于轻中度休克, 死亡组高于存活组, 对休克存活组 18 例血浆 ET 水平进行动态观察,发现随着休克的纠正及病情好转, 血浆 ET 也逐渐恢复正常.( 2) G -菌感染儿血 浆 ET 高于 G+菌感染儿.( 3)休克时 ET 与 BUN 、血 Cr 呈正相关, 与 PO2、BE 呈负相关,提示 ET 参与新 生儿败血症休克的病理生理过程,并与疾病的严重程度及预后有关.
关键词： 内皮素;  新生儿;  休克;  败血症     
Abstract: The concentration of plasma endothelin( ET)is measured by radioimmunoassay in 40 newborn babies with septic shock. The results show that:①the valuesof ET are markedly increased in shock patients comparedw ith those in control, those in bad shock with in mild, those in bad group with those still alive. By researchiny ET of 18 patients still alive,It is found that ET becomes normal step by step as shock disappears.②ET in G -infection patients is higher than that in G+ infection patients.③In shock patients, ET is in proportion either pasitively to BUN ,Cr or negtively to PO2,BE. It indicates that ET may be involved in pathophysiological processes of newborn septic shock and is correlated with severness of disease and prognosis.
Key words: endothelin    newborn babies    shock    septicemia
出版日期: 2017-12-06
CLC:  :R722. 131  
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杨仁志　冯建华　

引用本文:

杨仁志　冯建华　. 新生儿败血症休克血浆内皮素水平的研究 [J]. 浙江大学学报（理学版）, .

Yang Renzhi Feng Jianhua. Studies on the Plasma Endothelin in Newborn Babies with Septic Shock . Journal of Zhejiang University (Science Edition), .

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https://www.zjujournals.com/sci/CN/    或    https://www.zjujournals.com/sci/CN/Y1998/V25/I4/100

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