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Journal of ZheJiang University(Medical Science)  2007, Vol. 36 Issue (5): 509-514    DOI: 10.3785/j.issn.1008-9292.2007.05.018
    
Genetic imprinting and embryonic development
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Published: 25 September 2007
Cite this article:

. Genetic imprinting and embryonic development. Journal of ZheJiang University(Medical Science), 2007, 36(5): 509-514.

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http://www.zjujournals.com/med/10.3785/j.issn.1008-9292.2007.05.018     OR     http://www.zjujournals.com/med/Y2007/V36/I5/509


基因印记与胚胎发育

基因印记的擦除、建立和维持是正常胚胎发育的基础,这一过程的实现主要有赖于各种DNA甲基转移酶的准确表达和密切合作,多种遗传综合征和胚胎发育缺陷与基因印记异常有关.基因印记对原始生殖细胞胞核全能性、配子成熟、胚胎生长发育、胎盘结构和功能,以及出生后个体的生长发育均有重要意义.

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