In most species, calcium waves in the oocyte are considered common phenomena in the activation of eggs. However, the mechanism of calcium waves has not yet been clarified. By collaborating with biologists studying Caenorhabditis elegans (C. elegans), which is widely used as a model organism, we observed that the following requirements must be satisfied to form a useful hypothesis based on calcium waves captured using high-speed in vivo imaging: (1) the ability to obtain an overview of how the calcium waves are propagated and (2) the ability to understand the propagation of waves in a narrow region. However, conventional visualization methods cannot satisfy these requirements simultaneously. Therefore, we propose a visual analytics system that allows users to understand and explore calcium wave images using cross-correlation analysis of the time-series data of the Ca2+ fluorescence intensity at each point. The interface of this system comprises an overview visualization, a detail visualization, and user interactions to satisfy these requirements and realize exploratory visualization. Some views present an overview visualization that displays the clustering results of a directed graph calculated using cross-correlation analysis. These views enable the users to understand the overview of wave propagation, thereby helping users find a region of interest. The detail visualization shows the relationship between the region of interest and other areas. Furthermore, users can use the proposed system with overview-detail and brush-link exploration to assign meaning to the region of interest and construct a hypothesis for its role. In this paper, we demonstrate how the proposed visual analytics approach works and how new hypotheses can be formed using the analysis of C. elegans calcium waves.

Audit logs are different from other software logs in that they record the most primitive events (i.e., system calls) in modern operating systems. Audit logs contain a detailed trace of an operating system, and thus have received great attention from security experts and system administrators. However, the complexity and size of audit logs, which increase in real time, have hindered analysts from understanding and analyzing them. In this paper, we present a novel visual analytics system, LongLine, which enables interactive visual analyses of large-scale audit logs. LongLine lowers the interpretation barrier of audit logs by employing human-understandable representations (e.g., file paths and commands) instead of abstract indicators of operating systems (e.g., file descriptors) as well as revealing the temporal patterns of the logs in a multi-scale fashion with meaningful granularity of time in mind (e.g., hourly, daily, and weekly). LongLine also streamlines comparative analysis between interesting subsets of logs, which is essential in detecting anomalous behaviors of systems. In addition, LongLine allows analysts to monitor the system state in a streaming fashion, keeping the latency between log creation and visualization less than one minute. Finally, we evaluate our system through a case study and a scenario analysis with security experts.